Table 5.
Participant-rated clinical global impression of change in overall health
| Adaptive pacing therapy (n=159) | Cognitive behaviour therapy (n=161) | Graded exercise therapy (n=160) | Specialist medical care alone (n=160) | ||
|---|---|---|---|---|---|
| Change from baseline | |||||
| 12 weeks | 153 (96%) | 153 (95%) | 151 (94%) | 151 (94%) | |
| Positive change | 20 (13%) | 32 (21%) | 37 (25%) | 7 (5%) | |
| Minimum change | 126 (82%) | 113 (74%) | 111 (74%) | 133 (88%) | |
| Negative change | 7 (5%) | 8 (5%) | 3 (2%) | 11 (7%) | |
| 24 weeks | 155 (97%) | 149 (93%) | 148 (93%) | 151 (94%) | |
| Positive change | 37 (24%) | 56 (38%) | 54 (37%) | 28 (19%) | |
| Minimum change | 111 (72%) | 82 (55%) | 89 (60%) | 107 (71%) | |
| Negative change | 7 (5%) | 11 (7%) | 5 (3%) | 16 (11%) | |
| 52 weeks | 153 (96%) | 147 (91%) | 152 (95%) | 152 (95%) | |
| Positive change | 47 (31%) | 61 (41%) | 62 (41%) | 38 (25%) | |
| Minimum change | 96 (63%) | 77 (52%) | 80 (53%) | 100 (66%) | |
| Negative change | 10 (7%) | 9 (6%) | 10 (7%) | 14 (9%) | |
| Odds ratio (positive change vs negative or minimum changes) | |||||
| Compared with specialist medical care | 1·3 (0·8–2·1); p=0·31 | 2·2 (1·2–3·9); p=0·011 | 2·0 (1·2–3·5); p=0·013 | .. | |
| Compared with adaptive pacing therapy | .. | 1·7 (1·0–2·7); p=0·034 | 1·5 (1·0–2·3); p=0·028 | .. | |
Data are n (%) or odds ratio (95% CI). Comparisons made at 52 weeks were taken from the final adjusted models. Positive change was defined as very much better or much better. Minimum change was defined as a little better, no change, or a little worse. Negative change was defined as much worse or very much worse.