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The cellular uptake of OND mediated by Tween cationic niosomes. Each experiment was performed in triplicate and the values were expressed as mean ± S.D. Statistical analyses were performed using Student’s t-test. Tw85 niosomes was with the highest efficiency among the Tween cationic niosomes. The result showed that higher hydrophilic the Tween was, the less cellular uptake efficient. Note: 1) vs other three groups, p<0.05; 2) vs CL groups, p<0.05.
