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. 2011 Apr;9(2):184–190. doi: 10.1089/adt.2010.0298

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Copyright 2011, Mary Ann Liebert, Inc.

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Fig. 3. — Comparison of assay formats by EC₅₀ values derived for Ribavirin. Data are plotted as % Inhibition of CPE versus log [μM]. (A) EC₅₀ is 36.7 ± 1.7 μM for Ribavirin using the FIC assay. (B) EC₅₀ 31.7 ± 1.8 μM for Ribavirin using the virus assay. EC₅₀ values and standard deviations were calculated based on % Inhibition of CPE at 10 concentrations, n = 5, using the four-parameter Levenburg-Marquardt algorithm with the minimum and maximum parameters locked at 0 and 100, respectively. EC₅₀, effective concentration 50%; FIC, frozen infected cell.