Table 2.

Exposure of compound 2 from s.i.d. dose.

Dose (mg/kg) (N ≥ 3)	Frequency	C max (μM)	AUC (μM*hr)	AUC/Dose ± SD (μM∗hr/mg/kg)
300	Once a day	10.6 ± 2.8	167 ± 36	0.565 ± 0.120
600	Once a day	12.9 ± 1.2	232 ± 29	0.387 ± 0.049
1000	Once a day	14.4 ± 2.2	273 ± 66	0.273 ± 0.066