Table 3.

Predictors of the broader phenotype in relatives (1295 relatives)

Predictor	Odds ratio	95% CI	P
Feature in relatives
Gender (female)	0.48	0.30–0.80	0.004
Degree	0.38	0.27–0.55	<0.0001
Parenthood	0.46	0.25–0.84	0.01
Feature in proband
Autism severity	1.1	1.0–1.2	0.02
Birth suboptimality score	1.2	1.2–1.3	0.01
Congenital anomaly score	0.8	0.7–0.9	<0.001
Epilepsy in proband	1.8	1.2–2.9	0.01