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. 2011 Mar 2;6:381–386. doi: 10.2147/IJN.S13249

Figure 2.

Figure 2

A schematic illustration of the prefunction for the nanoparticles surface. Four chemical structures: A) EDC·HCl; B) S-NHS; C) 1-OT; D) 11-MUA. E) A mixed monolayer of 1-OT and 11-MUA is formed on the exposed surfaces of the Ag nanoparticles. EDC is a zero length coupling agent and can couple the amine groups on the antibody to the carboxyl groups on 11-MUA.