Table 3.
Slopes and y-intercepts: Linear regression of metabolites vs. percent GM
| MRJ (n=13) | NU (n=10) | F1,23 | P | ||
|---|---|---|---|---|---|
| Slope | Cho/Cr | −.017±.015** | −.030±.023** | 2.82 | .11 |
| mI/Cr | −.002±.010 | −.006±.008** | 4.76 | .04* | |
| NAA/Cr | .002±.017 | .003±.013 | 0.01 | ns | |
| NAA + NAAG/Cr | −.002±.021 | −.004±.016 | 0.09 | ns | |
| Glu/Cr | −.001±.013 | −.003±.009 | .01 | ns | |
| Gln/Cr | −.002±.017 | .003±.006 | 1.97 | .18 | |
| y-intercept | Cho/Cr WM | 0.39±0.09 | 0.46±0.10 | 2.43 | .14 |
| Cho/Cr GM | 0.23±0.08 | 0.17±0.13 | 2.66 | .12 | |
| mI/Cr WM | 1.08±0.44 | 1.39±0.37 | 10.36 | .005* | |
| mI/Cr GM | 0.88±0.61 | 0.81±0.48 | 1.61 | ns |
Data represent group averages (± SD) of the slope of the linear regression of metabolites normalized to Cr and %GM, and estimated y-intercept values for metabolite ratios at 0% GM (WM) and at 100% GM.
Indicates statistically significant group difference and
indicates slope significantly different from zero, P < .05. Abbreviations: Cho, Choline; mI, myo-Inositol; NAA, N-acetyl-aspartate; NAA + NAAG, N-acetyl-aspartate + N-acetyl-aspartyl-glutamate; Glu, glutamate; Gln, glutamine; WM, white matter; GM, grey matter