Table 2.
Year | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2008 | 2009 | 2010 | 2011 | 2012 | |||||||||
| |||||||||||||
Molecule | Reporteda | Fast d4T phase-outa | Slower d4T phase-outa | Difference between scenarios | Fast d4T phase-outa | Slower d4T phase-outa | Difference between scenarios | Fast d4T phase-outa | Slower d4T phase-outa | Difference between scenarios | Fast d4T phase-outa | Slower d4T phase-outa | Difference between scenarios |
d4T | 1.92 | 2.12 | 2.23 | 5% | 2.00 | 2.41 | 20% | 1.68 | 2.48 | 47% | 1.18 | 2.43 | 105% |
ZDV | 1.26 | 1.67 | 1.60 | −4% | 2.15 | 1.92 | −11% | 2.68 | 2.23 | −17% | 3.26 | 2.56 | −22% |
3TC | 3.23 | 4.03 | 4.00 | −1% | 4.73 | 4.70 | −1% | 5.40 | 5.36 | −1% | 6.06 | 5.96 | −2% |
NVP | 2.00 | 2.34 | 2.30 | −2% | 2.70 | 2.61 | −3% | 3.00 | 2.85 | −5% | 3.26 | 3.00 | −8% |
EFV | 1.15 | 1.72 | 1.72 | 0% | 2.14 | 2.16 | 1% | 2.59 | 2.64 | 2% | 3.08 | 3.14 | 2% |
ABC | 0.05 | 0.06 | 0.07 | 12% | 0.06 | 0.09 | 46% | 0.05 | 0.11 | 115% | 0.04 | 0.14 | 297% |
ddI | 0.08 | 0.09 | 0.10 | 9% | 0.09 | 0.12 | 35% | 0.07 | 0.14 | 95% | 0.03 | 0.15 | 360% |
IDV | 0.01 | 0.01 | 0.01 | 36% | 0.01 | 0.02 | 142% | 0.01 | 0.03 | 345% | 0.01 | 0.05 | 750% |
LPV | 0.18 | 0.22 | 0.22 | 0% | 0.28 | 0.28 | 1% | 0.34 | 0.35 | 3% | 0.41 | 0.43 | 4% |
TDF | 0.21 | 0.54 | 0.50 | −8% | 1.02 | 0.89 | −13% | 1.63 | 1.38 | −15% | 2.37 | 1.99 | −16% |
FTC | 0.10 | 0.25 | 0.24 | −2% | 0.38 | 0.36 | −4% | 0.55 | 0.51 | −6% | 0.74 | 0.69 | −7% |
NFV | 0.01 | 0.01 | 0.01 | −6% | 0.01 | 0.01 | −20% | 0.01 | 0.00 | −45% | 0.00 | 0.00 | −100% |
RTV | 0.16 | 0.22 | 0.22 | 2% | 0.28 | 0.29 | 6% | 0.34 | 0.38 | 10% | 0.41 | 0.48 | 15% |
SQV | 0.00 | 0.00 | 0.00 | 69% | 0.00 | 0.01 | 228% | 0.00 | 0.01 | 448% | 0.00 | 0.02 | 730% |
ATV | 0.03 | 0.03 | 0.03 | 8% | 0.03 | 0.04 | 28% | 0.04 | 0.06 | 54% | 0.04 | 0.08 | 88% |
aUnits are millions of person-years of antiretroviral therapy.