Table 3.
QoL over time and changes over time by age groupa
| Median (interquartile range) | Baseline | 1.5 months | 3 months | 4.5 months | 6 months | 12 months |
| N = 112 | N = 101 | N = 97 | N = 93 | N = 91 | N = 78 | |
| Global health status/QoLb | 66.7 (50–83.3) | 66.7 (50–83.3) | 66.7 (50.0–83.3) | 66.7 (50–83.3) | 75.0 (50–91.7) | 75.0 (58.3–83.3) |
| 65- to 74-year olds | 75.0 (58.3–91.7) | 66.7 (50.0–83.3) | 66.7 (50.0–83.3) | 66.7 (50–83.3) | 66.7 (50.0–91.7) | 75.0 (58.3–91.7) |
| 75 and older | 66.7 (50–83.3) | 66.7 (50–83.3) | 66.7 (50.0–83.3) | 66.7 (50–83.3) | 75.0 (54.2–83.3) | 75.0 (58.3–83.3) |
| Functional scalesb | ||||||
| Emotional functioning | 80.6 (66.7–91.7) | 83.3 (66.7–91.7) | 83.3 (66.7–100) | 83.3 (66.7–100) | 91.7 (66.7–100) | 91.7 (75.0–100) |
| 65- to 74-year olds | 83.3 (62.5–91.7) | 83.3 (66.7–91.7) | 83.3 (66.7–100) | 83.3 (66.7–100) | 91.7 (75.0–100) | 91.7 (75.0–100) |
| 75 and older | 77.8 (66.7–95.8) | 83.3 (66.7–91.7) | 75.0 (66.7–100) | 79.2 (66.7–100) | 87.5 (66.7–100) | 83.3 (75.0–100) |
| Physical functioning | 93.3 (70–100) | 86.7 (66.7–93.3) | 86.7 (73.3–100) | 86.7 (66.7–100) | 86.7 (73.3–100) | 93.3 (80.0–100) |
| 65- to 74-year olds | 93.3 (80–100) | 86.7 (66.7–93.3) | 86.7 (78.3–95.0) | 86.7 (70.0–96.7) | 93.3 (73.3–100) | 90 (80.0–100) |
| 75 and older | 86.7 (61.7–100) | 86.7 (70.0–93.3) | 86.7 (60.0–100) | 86.7 (66.7–100) | 86.7 (75.0–100) | 93.3 (66.7–100) |
| Role functioning | 100 (83.3–100) | 83.3 (66.7–100) | 100 (66.7–100) | 100 (66.7–100) | 100 (66.7–100) | 100 (83.3–100) |
| 65- to 74-year olds | 100 (83.3–100) | 83.3 (66.7–100) | 100 (66.7–100) | 83.3 (66.7–100) | 100 (66.7–100) | 100 (66.7–100) |
| 75 and older | 100 (66.7–100) | 83.3 (66.7–100) | 100 (66.7–100) | 100 (66.7–100) | 100 (83.3–100) | 100 (83.3–100) |
| Cognitive functioning | 100 (83.3–100) | 83.3 (83.3–100) | 91.7 (83.3–100) | 100 (83.3–100) | 100 (83.3–100) | 100 (83.3–100) |
| 65- to 74-year olds | 100 (75.0–100) | 91.7 (83.3–100) | 83.3 (75.0–100) | 100 (83.3–100) | 100 (83.3–100) | 83.3 (83.3–100) |
| 75 and older | 91.7 (83.3–100) | 83.3 (66.7–100) | 100 (83.3–100) | 100 (83.3–100) | 83.3 (83.3–100) | 100 (83.3–100) |
| Social functioning | 100 (83.3–100) | 83.3 (58.3–100) | 100 (66.7–100) | 100 (66.7–100) | 100 (83.3–100) | 100 (83.3–100) |
| 65- to 74-year olds | 100 (83.3–100) | 83.3 (50.0–100) | 100 (66.7–100) | 83.3 (66.7–100) | 100 (66.7–100) | 100 (83.3–100) |
| 75 and older | 100 (83.3–100) | 83.3 (66.7–100) | 100 (66.7–100) | 100 (66.7–100) | 100 (83.3–100) | 100 (83.3–100) |
| Symptom scalesc | ||||||
| Fatigue | 22.2 (11.1–38.9) | 33.3 (22.2–55.6) | 33.3 (11.1–44.4) | 22.2 (11.1–44.4) | 22.2 (11.1–33.3) | 22.2 (0–33.3) |
| 65- to 74-year olds | 22.2 (0–33.3) | 27.8 (11.1–55.6) | 33.3 (11.1–44.4) | 22.2 (11.1–44.4) | 22.2 (11.1–44.4) | 22.2 (0–33.3) |
| 75 and older | 22.2 (11.1–44.4) | 33.3 (22.2–55.6) | 33.3 (22.2–44.4) | 27.8 (11.1–52.8) | 22.2 (11.1–33.3) | 22.2 (0–44.4) |
| Nausea–vomiting | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| 65- to 74-year olds | 0 (0–0) | 0 (0–16.7) | 0 (0–0) | 0 (0–16.7) | 0 (0–0) | 0 (0–0) |
| 75 and older | 0 (0–0) | 0 (0–0) | 0 (0–16.7) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| Pain | 16.7 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) | 0 (0–33.3) | 16.7 (0–33.3) |
| 65- to 74-year olds | 16.7 (0–25.0) | 16.7 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) |
| 75 and older | 8.3 (0–33.3) | 16.7 (0–33.3) | 16.7 (0–33.3) | 0 (0–33.3) | 0 (0–29.2) | 16.7 (0–33.3) |
| Dyspnoea | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) |
| 65- to 74-year olds | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 33.3 (0–33.3) | 0 (0–33.3) |
| 75 and older | 0 (0–33.3) | 33.3 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) |
| Insomnia | 33.3 (0–50) | 33.3 (0–33.3) | 33.3 (0–33.3) | 33.3 (0–33.3) | 0 (0–33.3) | 33.3 (0–33.3) |
| 65- to 74-year olds | 33.3 (0–33.3) | 33.3 (0–33.3) | 33.3 (0–33.3) | 33.3 (0–33.3) | 33.3 (0–33.3) | 33.3 (0–33.3) |
| 75 and older | 33.3 (0–66.7) | 33.3 (0–33.3) | 33.3 (0–66.7) | 16.7 (0–33.3) | 0 (0–66.7) | 0 (0–33.3) |
| Appetite loss | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) |
| 65- to 74-year olds | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) |
| 75 and older | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–25.0) | 0 (0–33.3) |
| Constipation | 0 (0–33.3) | 0 (0–33.3) | 0 (0–0) | 0 (0–33.3) | 0 (0–0) | 0 (0–33.3) |
| 65- to 74-year olds | 0 (0–0) | 0 (0–33.3) | 0 (0–0) | 0 (0–33.3) | 0 (0–0) | 0 (0–0) |
| 75 and older | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) | 0 (0–33.3) |
| Diarrhea | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| 65- to 74-year olds | 0 (0–0) | 0 (0–0) | 0 (0–33.3) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| 75 and older | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| Financial problems | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| 65- to 74-year olds | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
| 75 and older | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) | 0 (0–0) |
QoL, quality of life.
a
At baseline, there were sixty-five 65- to 74-year olds and forty-five ≥75 years, and at 12 months there were forty-eight 65- to 74-year olds and thirty-one ≥75 years.
b
For the global health status/QoL and functional scales, 0 = poor functioning and 100 = highest level of functioning.
c
Symptom scales 0 = no symptoms and 100 = maximum symptomatology.