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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Vaccine. 2010 Dec 16;29(6):1194–1200. doi: 10.1016/j.vaccine.2010.12.002

Table VII.

Tumor protection in outbred New Zealand White rabbits challenged with CRPV DNA containing the HPV16E7 82-90 epitope inserted in the E7 gene or wild-type CRPV DNA after three immunizations with the HPV16E7/82-90 epitope DNA vaccine.

Rabbits DNA Challenged Sites Protection Ratea (%)
1 HLA-A2.1 (N = 2) WT CRPV 16 0/16 (0%)b
2 HLA-A2.1 (N = 3) E7 Ins 82 24 19/24 (79%)
a

Protection rate, papilloma-free sites/challenge sites (eight sites/each construct/each rabbit);

b

p = 0.001 vs group 2, Fisher’s exact test.