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Effect of extracellular K+ on phosphatidylserine (PS) exposure in red blood cells (RBCs) from sickle cell patients. RBCs were incubated for 18 hours with extracellular [Ca2+] of 5 mM under oxygenated (20% O2) or deoxygenated (1% O2) conditions in either low K+-containing (extracellular [K+] of 5 mM) saline or high K+-containing (90 mM [K+]) saline. Histograms represent means ± S.E.M. (n = 3). *P < .001 compare to LK oxy; #N.S. cf. LK oxy.
