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| +/+ | +/– | –/– | (Observed –/–)/(expected –/–) | |
|---|---|---|---|---|
| A Offspring of tia-1+/– × tia-1+/– cross | ||||
| Adult mice | 38 | 67 | 16 | 16/35 (46%) |
| Embryos (E12.5–E16.5) | 18 | 30 | 14 | 14/16 (89%) |
| B Offspring of tia-1+/– × tia-1–/– cross | ||||
| Embryos (E9.5–E11.5) | 31 | 32 | 32/31 (103%) |
aTIA-1 deficiency is partially lethal. Genotype distribution of (A) tia-1+/– × tia-1+/– progeny and (B) tia-1+/– × tia-1–/– progeny of adult mice and embryos of different developmental stages.
