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. Author manuscript; available in PMC: 2011 Mar 29.
Published in final edited form as: J Neurovirol. 2009 Dec;15(5-6):434–438. doi: 10.1080/13550280903168131

Figure 1.

Figure 1

Twelve-hour caspase 3/7 activity of HIV (BaL) (500 pg/ml)–exposed human primary neurons in the presence and absence of GSK3β inhibitors A and B. Human primary neurons were incubated for 12 h in the presence and absence of HIV (BaL) at 500 pg/ml with and without A (1 µM,100 nM,10nM) and B (500 pM, 5 nM, and 50nM). Exposure to HIV (BaL) resulted in a significant increase in caspase 3/7 activity (P= .022). Coexposure of HIV with all concentrations of A significantly decreased caspase 3,7 activity from HIV alone (P <.01). Coexposure of compound B at 50 nM also produced significant decreases in caspase 3,7 activity (P < .01). Data represented are% change in caspase 3,7 activity from controls. *Significant at P < .05.