Table 2.

Concentrations of airway fluid biomarkers in children with moderate (n = 20) and severe (n = 35) asthma

	Raw concentration in the BAL fluid supernatant			Concentration per mL of ELF
Biomarker	Moderate asthma	Severe asthma	p value for BAL*	Moderate asthma	Severe asthma	p value for ELF*
GSSG (nmol/L BAL, µ/nmol/L ELF)	334 (36–1352)	262 (7–1510)	0.628	37 (3–408)	24 (2–178)	0.292
GSSG (nmol/L BAL, µmol/L ELF)	134 (26–929)	447(42–3113)	0.006	13 (3–71)	32 (2–201)	0.015
MDA (nmol/L BAL, µmol/L ELF)	565 (165–980)	860 (165–3563)	0.039	37 (8–104)	54(11–162)	0.037
8-OH-dg (pg/mL BAL, ng/mL ELF)	168 (29–667)	537 (30–5056)	0.011	13 (2–231)	24 (3–650)	0.031
IL-8 (pg/mL BAL, ng/mL ELF)	15 (4–104)	32 (6–1984)	0.042	2 (0–4)	3 (1–137)	0.050

Data are expressed as the median (range).

^*After logarithmic transformation.