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. Author manuscript; available in PMC: 2011 Mar 29.
Published in final edited form as: J Immunol. 2009 Dec 16;184(2):615–623. doi: 10.4049/jimmunol.0902408

FIGURE 3.

FIGURE 3

Increased expression of IL-4Rα is determined by the local environment. A, IL-4Rα expression on CD4+ cells from mesLNs or pooled nondraining lymph nodes (cervical, axial, brachial, inguinal, and popliteal) was compared 14 d after oral H. polygyrus infection and (B) from draining and contralateral popliteal lymph nodes 7 d after s.c. immunization in the footpad with H. polygyrus larvae.C, CD4+ IL-4Rαhi cells were isolated from mesLNs 14 d after H. polygyrus infection and transferred into either 14 d infected or naive recipients. CD4+ cells in the recipient mesLNs were analyzed 24 h later by flow cytometry. Data are representative of three or more independent experiments.