Table 1.

Effect of NETKO on densities of sets of enteric neurons

Type of neuron	Packing density (neurons/mm2)		p
	WT	NETKO
Total (HuC/D)	261 ± 17	187 ± 15	<0.02
Serotonergic (5-HT)	0.94 ± 0.09	0.34 ± 0.08	<0.005
Calretinin	84.0 ± 6.4	56.8 ± 5.7	<0.02
Nitrergic (nNOS)	17.7 ± 3.4	26.3 ± 3.4	NS
Dopaminergic (TH)	2.1 ± 0.5	1.9 ± 0.5	NS

Data were derived from analyses of the small intestinal myenteric plexus of five WT and five NETKO mice. In each preparation of each type of immunostainings, neurons were counted in 10 mm² of tissue in a flat whole mount of longitudinal muscle with attached myenteric plexus.