Table 1.

Framingham Risk Score Characteristics at Baseline Among White Participants

	Men n = 1495			Women n = 2156
	Baseline Value	β (P value)*		Baseline Value	β (P value)*
Age, y, mean (SD)	73.3 (5.7)	0.043 (0.0002)		72.3 (5.4)	0.18 (0.45)
Current smoker	10%	-0.19 (0.44)		12%	0.49 (0.01)
LDL, mg/dL, mean (SD)	124 (33)	NA§		135 (37)	NA§
LDL category
< 100	24.4%	-0.13 (0.45)		16.8%	-0.18 (0.38)
100-129	35.0%	reference		30.7%	reference
130-159	28.0%	0.10 (0.49)		29.4%	-0.04 (0.80)
160-189	10.0%	0.22 (0.29)		16.2%	0.10 (0.57)
> = 190	2.7%	-0.19 (0.65)		6.9%	-0.23 (0.41)
HDL, mg/dL, mean (SD)	48 (13)	NA§		59 (16)	NA§
HDL category
< 35	11.4%	0.16 (0.47)		1.9%	-0.24 (0.65)
35-44	34.1%	0.090 (0.60)		14.2%	0.15 (0.43)
45-49	18.3%	reference		13.0%	0.20 (0.30)
50-59	20.5%	-0.21 (0.29)		26.9%	reference
> = 60	15.6%	-0.030 (0.89)		43.9%	-0.18 (0.27)
Blood pressure category†
Optimal	23.3%	-0.31 (0.14)		23.8%	0.22 (0.34)
Normal	18.5%	reference		18.0%	reference
high normal	20.2%	0.30 (0.13)		19.2%	0.46 (0.05)
HTN stage I	23.8%	0.39 (0.04)		26.2%	0.58 (0.007)
HTN stage II-IV	14.1%	0.21 (0.33)		12.8%	0.95 ( 0.00005)
Diabetes‡	13.0%	0.57 (0.0006)		8%	0.66 (0.001)

* Coefficients from Cox regression model of Framingham Risk Score (FRS) variables.

† Optimal (systolic < 120 mm Hg and diastolic < 80 mm Hg), normal blood pressure (systolic 120 to 129 mm Hg or diastolic 80 to 84 mm Hg), high normal blood pressure (systolic 130 to 139 mm Hg or diastolic 85 to 89 mm Hg), hypertension stage I (systolic 140 to 159 mm Hg or diastolic 90 to 99 mm Hg), and hypertension stage II-IV (systolic 160 or diastolic 100 mm Hg). When systolic and diastolic pressures fell into different categories, the higher category was selected. Blood pressure categorization was made without regard to the use of antihypertensive medication.

‡ Fasting serum glucose ≥140 or taking insulin or oral hypoglycemic medications.

§ Continuous cholesterol measures are not included in the FRS model