Table 5.
Markers Added to FRS Model |
Number Reclassified (%) | Net Number Reclassified Correctly (NRI, P value) |
AUC (P value)* |
---|---|---|---|
9p21 | 50 (21.9) | 10 (0.182, 0.02) | 0.688 (0.07) |
KIF6 | no data† | no data† | no data† |
CRP | 48 (21.1) | -4 (0.006, 0.94) | 0.654 (0.92) |
CRP + 9p21 | 70 (30.7) | 10 (0.129, 0.16) | 0.675 (0.51) |
CRP + KIF6 | no data† | no data† | no data† |
9p21 + KIF6 | no data† | no data† | no data† |
CRP + 9p21 + KIF6 | no data† | no data† | no data† |
* P value for change in AUC from AUC of the FRS model (0.657)
†Risk for KIF6 cannot be calculated because none of the 15 African American men who were noncarriers of the KIF6 719Arg risk allele had an event.