Effect of donepezil. a–d, Mean choice accuracy (a), omissions (b), perseverative responses after a correct choice (c), and perseverative responses after an incorrect choice (d) of wild-type and 3xTgAD mice (n = 8 per genotype, age 42–44 weeks) 1 h after saline, 0.03 mg/kg donepezil, 0.01 mg/kg donepezil, and 0.03 mg/kg donepezil injections, at a stimulus duration of 0.8 s. *p < 0.05, simple main effect of genotype.