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. 2011 Mar 29;6(3):e17437. doi: 10.1371/journal.pone.0017437

Figure 4. Chronic RAS blockade reduces ACE expression and angiotensin II levels after ovariectomy.

Figure 4

Effects of chronic treatment of OVX rats with enalapril or valsartan on the protein level of angiotensin-converting enzyme (ACE) revealed by Western blot (A) and immunohistochemistry (B). Immunohistochemical staining of angiotensin II in the aortic vascular wall (C). Sections are counterstained with hematoxylin. Magnification ×400. Results are means±SEM of 4–6 experiments. Statistical significance is indicated by ** p<0.01 and *** p<0.001.