Table II.

Manometric and pH-metric profile

	Patients with GERD	Patients without GERD	P value
Manometric profile
LES
LES pressure (mm Hg)	25 (16–35)	30 (24–36)	.317
LES total length (cm)	2 (2–3)	3 (3)	.052
LES abdominal length (cm)	2 (1–2)	2 (2–3)	.084
Esophageal body
DEA (mm Hg)	46 (32–81)	90 (53–137)	.029
pH metric profile
Total time pH <4 (%)	9 (6–18)	1 (1–2)	.000001
Upright	8 (6–12)	2 (1–3)	.0004
Supine	9 (4–18)	0 (0)	.000003
Episodes >5 min	6 (4–11)	1 (0–1.1)	.000001
Longest episode (minutes)	24 (16–38)	6 (3–11)	.00004
Total episodes	57 (35–84)	13 (11–26)	.0001
DeMeester score (normal: <14.7)	31 (22–65)	5 (4–9)	.000001
Esophageal clearance (sec)
Total mean acid clearance time	181 (132–280)	52 (30–106)	.0002
Upright	105 (87–149)	52 (30–106)	.101
Supine	236 (183–419)	0 (0–10)	.00002
Proximal pH sensor data
Total time pH <4 (normal: <1%)	0.9 (0.5–2.2)	0.2 (0–1.9)	.0004
Upright	0.4 (0.2–2.4)	0.3 (0–2.9)	.238
Supine	0.7 (0–1.9)	0	.0034

Data are presented as medians (interquartile ranges).

DEA, Distal esophageal amplitude; GERD, gastroesophageal reflux disease; LES, lower esophageal sphincter.