Table 3.
Cell Type | HCN | Cav | Kv | Kir | # | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 3.1 | 3.2 | 3.3 | 1.4 | 3.4 | 4.1 | 4.2 | 4.3 | 2.1 | 2.2 | 2.3 | 2.4 | ||
I | 0 | + | 0 | + | 0 | 0 | 0 | 0 | 0 | 0 | + | + | + | 0 | 0 | 0 | 5/6 |
II | + | + | + | + | + | 0 | 0 | 0 | 0 | 0 | + | 0 | + | 0 | + | 0 | 15/34 |
+ | + | + | 0 | + | 0 | 0 | 0 | 0 | 0 | + | 0 | 0 | 0 | +/− | 0 | 8/34 | |
+ | + | 0 | 0 | + | 0 | + | 0 | 0 | 0 | 0 | + | 0 | 0 | + | 0 | 11/34 | |
III | 0 | 0 | 0 | + | 0 | 0 | + | 0 | 0 | 0 | + | 0 | +/− | + | + | 0 | 9/11 |
Cells were first filtered according to their expression pattern for the HCN subunits. Subsequent filtering was determined by ≥ 80% expression (+), ~ 50% expression (+/−), and < 10% expression (0). Numbers in the far right column represent the number of cells for each subgroup that expressed all of the HCN channels indicated and ≥ 80% expression for two or more of the remaining α subunits.