Table III.
Composition of THC-SEFDDS Pellet Formulations with Different Weight Proportions of Sodium Starch Glycolate
| Ingredients | Formulations (% w/w) | |||
|---|---|---|---|---|
| F5 | F6a | F7 | F8 | |
| THC | 1.98 | 1.98 | 1.98 | 1.98 |
| Cremophor EL | 7.76 | 7.76 | 7.76 | 7.76 |
| Labrasol | 7.76 | 7.76 | 7.76 | 7.76 |
| Capryol 90 | 3.33 | 3.33 | 3.33 | 3.33 |
| Labrafac PG | 3.33 | 3.33 | 3.33 | 3.33 |
| Glyceryl behenate | 55 | 55 | 55 | 55 |
| Silicon dioxide | 0.15 | 0.15 | 0.15 | 0.15 |
| Microcrystalline cellulose | 18.19 | 17.39 | 16.59 | 14.99 |
| Pregelatinized starch | 2.5 | 2.5 | 2.5 | 2.5 |
| Sodium starch glycolate | 0 | 0.8 | 1.6 | 3.2 |
THC tetrahydrocurcumin, THC-SEFDDS tetrahydrocurcumin-self-emulsifying floating drug delivery system
aThe composition of formulation F6 is identical to that of formulation F2 (Table I)