Table 2.
Age-weighted comparison of anthropometric and blood pressure data for the 21-hydroxylase deficiency United Kingdom CaHASE cohort patients (n = 199) with the normal United Kingdom population based on HSE data
| Variable | CAH | HSE | P, CAH vs. HSE | P, CAH subgroup comparison |
|---|---|---|---|---|
| Height (cm) | ||||
| Male classic (n = 61) | 162 | 176 | <0.0001 | |
| Female classic (n = 103) | 152 | 162 | <0.0001 | <0.0001a |
| Female nonclassic (n = 31) | 157 | 162 | 0.0001 | 0.003b |
| BMI (kg/m2) | ||||
| Male classic (n = 61) | 27.2 | 27.2 | 1.0 | |
| Female classic (n = 103) | 32.9 | 26.7 | <0.0001 | 0.064a |
| Female nonclassic (n = 31) | 29.4 | 26.7 | 0.0064 | 0.24b |
| Waist circumference (cm) | ||||
| Male classic (n = 57) | 96.7 | 94.4 | 0.24 | |
| Female classic (n = 99) | 99.5 | 85.9 | <0.0001 | 0.94a |
| Female nonclassic (n = 31) | 92.6 | 85.9 | 0.0043 | 0.36b |
| Sitting systolic blood pressure (mm Hg) | ||||
| Male classic (n = 61) | 126 | 130 | 0.04 | |
| Female classic (n = 102) | 124 | 124 | 1.0 | 0.21a |
| Female nonclassic (n = 30) | 123 | 124 | 0.73 | 0.57b |
| Sitting diastolic blood pressure (mm Hg) | ||||
| Male classic (n = 61) | 77.5 | 75.4 | 0.16 | |
| Female classic (n = 102) | 77.9 | 73.7 | 0.0002 | 0.96a |
| Female nonclassic (n = 30) | 74.4 | 73.7 | 0.54 | 0.48b |
a
Classic male vs. classic female CAH patients.
b
Classic female vs. nonclassic female CAH patients.