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Cop-1-reactive T cells protect RGCs from glutamate toxicity. Immediately after injection of glutamate (200 nmol), mice were injected with Cop-1-reactive T cells or with PBS. Dye application, preparation, and counting of RGCs and calculation of RGC survival were as described for Fig. 1. Significantly more labeled RGCs were seen in the retinas of mice injected with Cop-1-reactive T cells than in the retinas of PBS-injected control mice (**, P < 0.0007, Student's t test).
