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Schematic biosynthetic pathway for a variety of isoquinoline alkaloids. 6-OMT, S-adenosyl-L-methionine:norcoclaurine 6-O-methyltransferase; 4′-OMT, S-adenosyl-L-methionine:3′-hydroxy-N-methylcoclaurine 4′-O-methyltransferase; SMT, S-adenosyl-L-methionine:scoulerine 9-O-methyltransferase; AdoMet, S-adenosyl-L-methionine; AdoHcy, S-adenosyl-L-homocysteine.
