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LC/MS analysis of the chimeric OMT reaction products using laudanosoline as a substrate. Upper panel; OMT reactions and their predicted ions in LC/MS analysis. Lower panels; Mass ion chromatogram of the reaction products. Product peaks with the same retention time and fragmentation ion as the 4′-OMT product (22 min, fragment of m/z = 178) are indicated by solid arrows, and those with the same parameters as 6-OMT (19 min, m/z = 192) are shown by open arrows.
