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General synthetic scheme of 4′-C-substituted-2′-deoxynucleoside (4′SdNs) from d-glucose. 4′SdN = 4′-C-substituted-2′-deoxynucleoside; 4′MN = 4′-C-methylnucleoside; 4′Md4N = 4′-C-methyl-2′,3′-didehydrodeoxynucleoside; 4′MddN = 4′-C-methyl-2′,3′-dideoxynucleoside.
