Fig. 6.
Analysis of the activity of LANA-dependent transcriptional repression by alanine substitution. Graphical representation of data from luciferase reporter assays. pGL3/7TR luciferase reporter and wt or mutant LANADBD plasmid were co-transfected. RLU values were normalized to total protein concentration as described previously (Renne et al., 2001). The percentage of suppression activity was compared with that of LANADBD wt, which was set to 100 %. Results are shown as means±sd from three independent experiments. (−)LANA, Negative control with no LANADBD.