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. Author manuscript; available in PMC: 2011 Mar 30.
Published in final edited form as: N Engl J Med. 2010 Jan 20;362(7):590–599. doi: 10.1056/NEJMoa0907355

Table 4.

Cost and effectiveness of salt reduction and hypertension treatment annually and cumulatively from 2010–2019

Costs and QALYs for the US population (SD) Costs and QALYs for the MediCare population(SD)

Cost of
intervention
(billions)
Change in
healthcare
cost
(billions)1
Change in
QALYs
(thousands)
Cost per
QALY
Healthcare
cost saved per
dollar spent
on intervention
Cost of
intervention
(billions)
Change in
healthcare
cost
(billions)
Change in
QALYs
(thousands)
Cost per
QALY
Healthcare
cost saved
per dollar
spent on
intervention

Population reduction in dietary salt

1gm/day
Low $0.32 −$4.1 (0.8) 74.9 (8.8) cost savings $15.4 (3.0) $0.3 −$0.7 (0.06) 46 (4.1) cost savings $2.5 (0.2)
High $0.32 −$7.0 (1.4) 120 (14.6) cost savings $26.1 (5.2) $0.3 −$1.0 (0.1) 72 (6.4) cost savings $3.8 (0.4)
3gms/day
Low $0.32 −$12.1 (2.4) 220 (26) cost savings $45.2 (9.1) $0.3 −$2.0 (0.2) 135.0 (12.2) cost savings $7.3 (0.7)
High $0.32 −$20.4 (4.1) 350 (42) cost savings $76.0 (15.4) $0.3 −$3.0 (0.3) 208.3 (18.6) cost savings $11.1 (1.1)

Blood pressure treatment with medications among hypertensive individuals 3

$19.5
(0.07)
−$14.2
(2.7)
360 (42) $15,800
(9,900)
$0.7 (0.1) $9.3
(0.03)
−$3.4
(0.3)
260
(24)
$23,300
(3,600)
$0.4 (0.04)

Cumulative cost and effectiveness of gradually reducing dietary salt over the decade from 2010–20194

1gm/day
Low $2.72 −$18.9 (3.8) 220 (27) cost savings $7.0 (1.4) $2.7 −$4.3 (0.4) 220 (20) cost savings $1.6 (0.2)
High $2.72 −$31.6 (6.5) 350 (43) cost savings $11.8 (2.4) $2.7 −$6.1 (0.6) 240 (21) cost savings $2.3 (0.2)
3gms/day
Low $2.72 −$56.9
(11.5)
650 (78) cost savings $21.2 (4.3) $2.7 −$12.1
(1.2)
420 (37) cost savings $4.5 (0.5)
High $2.72 −$95.6
(19.6)
1,000 (127) cost savings $35.6 (7.3) $2.7 −$18.
(1.9)
665 (58) cost savings $6.9 (0.7)
1

Healthcare costs for the US adults population age 35 years and older, discounted at 3% over the decade

2

$1 per person estimate per year for the cost of a population-wide regulatory approach to salt reduction based on the World Health Organization estimate, US population of 306,913,687 as of July 2009. http://www.census/gov, discounted at 3% over the decade

3

Treatment of all hypertensive individuals to the degree observed in clinical trials25.and cost effectiveness analysis24

4

Gradual reduction from 2010–2019, with one third of the total reduction achieved in 2012, a second 1/3 in 2015, and a third 1/3 in 2019