Skip to main content
. 2010 Oct;51(10):5190–5197. doi: 10.1167/iovs.10-5257

Figure 5.

Figure 5.

Brinzolamide provocative test results in rabbits with NBCe1knockdown. (A) Average (SD) of peak changes in corneal thickness 3 to 5 hours after topical application of two drops of 1% brinzolamide to both eyes. OD, control (injected with scrambled sequence). OS, >25% knockdown of NBCe1-shRNA. (B) Average (SD) of paired differences (OS-OD) in peak brinzolamide-induced corneal swelling measured at 2 and 3 weeks after injection in rabbits demonstrating <25% and >25% knockdown of NBCe1. *Significantly different from 0 (P < 0.005). Number of rabbits in each category is shown in parentheses.