Table 2.
Weeks | ID (IL-10 pg/mL) | ID/Rx (IL-10 pg/mL) |
---|---|---|
4 | 54.9 ± 17.9 | 73.0 ± 3.7 |
8 | 55.8 ± 1 | 74.4 ± 5.4 |
12 | ND | 164.1 ± 12.9* |
Tears were collected 6 weeks after disease induction (i.e., 4 weeks after AAV-IL-10 transduction and doxycycline feeding in ID/RX rabbits. ID rabbits were not transduced but were fed with doxycycline. Paired t-test was performed for within-group differences. Independent sample t-test was performed for comparison between AAV and ID groups. ND, not done.
Significant increase in 12 weeks.