Table 2.

ELISA of IL-10 Transgene Expression in Tears from ID and ID/Rx Rabbits

Weeks	ID (IL-10 pg/mL)	ID/Rx (IL-10 pg/mL)
4	54.9 ± 17.9	73.0 ± 3.7
8	55.8 ± 1	74.4 ± 5.4
12	ND	164.1 ± 12.9*

Tears were collected 6 weeks after disease induction (i.e., 4 weeks after AAV-IL-10 transduction and doxycycline feeding in ID/RX rabbits. ID rabbits were not transduced but were fed with doxycycline. Paired t-test was performed for within-group differences. Independent sample t-test was performed for comparison between AAV and ID groups. ND, not done.

^*Significant increase in 12 weeks.