Table 4. Genes involved in p53 signaling pathway induced by sulfur mustard at 24, 72 and 168 h post-exposure.

Gene name	Gene description	Fold change (SM)
		24 h	72 h	168 h
Akt2	v-akt murine thymoma viral oncogene homolog 2	1.78†	1.46*	1.41†
Bax	BCL2-associated X protein	3.38†	2.56†	2.23†
Ccnd1	Cyclin D1	1.87†	1.67*	1.67†
Ccng1	Cyclin G1	5.89†	3.30*	2.73*
Chek2	CHK2 checkpoint homolog (S. pombe)	−1.04	2.10†	1.79*
E2f1	E2F transcription factor 1	1.49	1.54	1.79*
Mdm2	Mdm2, transformed 3 T3 cell double minute 2, p53 binding protein	3.41†	1.87†	1.69*
Pik3c2g	Phosphoinositide-3-kinase, class 2, gamma polypeptide	−2.56†	−2.13*	−2.44†
Pik3cd	Phosphoinositide-3-kinase, catalytic, delta polypeptide	1.13	1.79	2.35*
Pik3cg	Phosphoinositide-3-kinase, catalytic, gamma polypeptide	1.29†	2.35*	3.12†
Pik3r5	Phosphoinositide-3-kinase, regulatory subunit 5, p101	2.01*	3.36*	4.14†
Pmaip1	Phorbol-12-myristate-13-acetate-induced protein 1	6.84†	3.93*	3.28*
Serpinb5	Serpin peptidase inhibitor, clade B (ovalbumin), member 5	−1.25	−1.39*	−2.06*
Serpine2	Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	1.95*	2.35*	3.99*
Trp53bp2	Tumor protein p53 binding protein2	−1.34*	−1.61*	−1.50
Trp53inp1	Tumor protein p53 inducible nuclear protein 1	2.75†	1.45†	1.36

^*p<0.05.

^†p<0.01.