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. Author manuscript; available in PMC: 2011 Mar 30.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Oct 7;234(2):156–165. doi: 10.1016/j.taap.2008.09.020

Table 5. Genes involved in NF-kB signaling pathway induced by sulfur mustard at 24, 72 and 168 h post-exposure.

Gene name Gene description Fold change (SM)

24 h 72 h 168 h
Akt2 v-akt murine thymoma viral oncogene homolog 2 1.78 1.46* 1.41
Ep300 E1A binding protein p300 −1.72* −2.13* −2.13*
Ghr Growth hormone receptor −1.66* −1.52* −1.18
Ikbkg v-Ha-ras Harvey rat sarcoma viral oncogene homolog 1.59* 1.80 1.48*
Il1b Interleukin 1, beta 35.29 34.18 51.94
Il1rn Interleukin 1 receptor antagonist 1.84 1.18 1.72
Irak3 Interleukin-1 receptor-associated kinase 3 2.78* 1.98 1.77*
Map3k7 Mitogen-activated protein kinase 8 1.66 1.3 1.74*
Nfkbia Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.66* 1.43 1.62*
Nfkbie Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.66 1.99 3.97*
Ngfb Nerve growth factor, beta polypeptide 13.52 11.37 6.15*
Pik3c2g Phosphoinositide-3-kinase, class 2, gamma polypeptide −2.56 −2.13* −2.44
Pik3cd Phosphoinositide-3-kinase, catalytic, delta polypeptide 1.13 1.79 2.35*
Pik3cg Phosphoinositide-3-kinase, catalytic, gamma polypeptide 1.29* 2.35* 3.12
Pik3r1 Phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) 1.03 −1.28* −1.39*
Pik3r5 Phosphoinositide-3-kinase, regulatory subunit 5, p101 2.01* 3.36* 4.14
Rras2 Related RAS viral (r-ras) oncogene homolog 2 1.94* 1.98* 1.79
Tgfa Transforming growth factor, alpha 1.57 2.36 2.24*
Tirap Toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.73* 1.60* 1.54*
Tlr1 Toll-like receptor 1 3.13 6.83 5.76
Tlr2 Toll-like receptor 2 2.25 3.34* 3.75*
Tlr3 Toll-like receptor 3 1.05 1.56 2.22
Tlr4 Toll-like receptor 4 1.64 1.85 1.93*
Tnfaip3 Tumor necrosis factor, alpha-induced protein 3 3.12 1.23 2.95
Traf3 TNF receptor-associated factor 3 1.65* 1.72 2.18*
*

p<0.05.

p<0.01.