Table 6. Genes involved in oxidative stress pathway induced by sulfur mustard at 24, 72 and 168 h post-exposure.
Gene name | Gene description | Fold change (SM) | ||
---|---|---|---|---|
24 h | 72 h | 168 h | ||
Fos | v-fos FBJ murine osteosarcoma viral oncogene homolog | 4.56* | 2.70† | 2.49* |
Gpx1 | Glutathione peroxidase 1 | 1.36 | 1.69 | 1.69* |
Gss | Glutathione synthetase | 1.48* | 1.51* | 1.40* |
Gsta2 | Glutathione S-transferase A5 | −2.70 | −1.92 | −3.70* |
Gstm2 | Glutathione S-transferase M1 | −1.52 | −1.15 | −1.59* |
Gstm1 | Glutathione S-transferase M5 | −1.60 | −1.77† | −2.00* |
Gstm5 | Glutathione S-transferase M3 (brain) | −1.33 | −1.12 | −1.82† |
Icam1 | Intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 3.86† | 2.78† | 3.81† |
Il6 | Interleukin 6(interferon, beta 2) | 26.54† | 12.51† | 16.61† |
Mgst1 | Microsomal glutathione S-transferase 1 | 1.24 | 1.36* | 2.83* |
Mpo | Myeloperoxidase | −1.18 | −2.63* | −9.09* |
Nfe2l2 | Nuclear factor (erythroid-derived 2)-like 2 | 1.33† | 1.36† | 1.35† |
Prdx3 | Peroxiredoxin 3 | 1.47 | 1.66† | 1.60† |
S100a9 | S100 calcium binding protein A9 | 60.60† | 71.55† | 52.98† |
Sod2 | Superoxide dismutase 2, mitochondrial | 1.46† | 1.15 | 1.43* |
Stat3 | Signal transducer and activator of transcription 3 | 2.04* | 1.67* | 1.85* |
Vcam1 | Vascular cell adhesion molecule 1 | 1.56 | 1.18 | 3.05* |
p<0.05.
p<0.01.