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. Author manuscript; available in PMC: 2011 Mar 30.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Oct 7;234(2):156–165. doi: 10.1016/j.taap.2008.09.020

Table 7. Genes involved in p38 MAPK pathway induced by sulfur mustard at 24, 72 and 168 h post-exposure.

Gene name Gene description Fold change (SM)

24 h 72 h 168 h
Creb1 cAMP responsive element binding protein 1 2.92* 9.38* 7.89*
Ddit3 DNA-damage-inducible transcript 3 1.62* 1.23 1.14
Eef2k Eukaryotic elongation factor-2 kinase −1.58 −1.80* −1.60
Fas Fas (TNF receptor superfamily, member 6) 2.88 2.10* 1.89
H3f3a H3 histone, family 3A 1.81* 1.05 1.17
H3f3b H3 histone, family 3B (H3.3B) 2.10* −1.13 −1.18
Il18 Interleukin 18 (interferon-gamma-inducing factor) −2.56* −1.08 −1.15
Il1b Interleukin 1, beta 35.29 34.18 51.94
Il1rn Interleukin 1 receptor antagonist 1.84 1.18 1.72
Irak3 Interleukin-1 receptor-associated kinase 3 2.78* 1.98 1.77
Map3k7 Mitogen-activated protein kinase kinase kinase 7 1.66 1.38* 1.74*
Mapk13 Mitogen-activated protein kinase 13 −1.56* 1.16 −1.30
Mef2a Myocyte enhancer factor 2A −1.00 1.41* 1.74*
Pla2g4b Phospholipase A2, group IVB (cytosolic) 1.48* 1.69* 1.40
Rps6ka4 Ribosomal protein S6 kinase, 90 kDa, polypeptide 4 1.87 1.92 1.60
Rps6ka5 Ribosomal protein S6 kinase, polypeptide 5 −1.61 −1.13 1.41
Stat1 Signal transducer and activator of transcription 1 1.49* 1.56* 1.73
Tgfb2 Transforming growth factor, beta 2 −1.70* −1.89* −1.68*
Tgfb3 Transforming growth factor, beta 3 −4.17 −1.67 −1.54
Tradd TNFRSF1A-associated via death domain 1.54 1.33 1.22
*

p<0.05.

p<0.01.