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. Author manuscript; available in PMC: 2011 Mar 30.
Published in final edited form as: Toxicol Appl Pharmacol. 2008 Oct 7;234(2):156–165. doi: 10.1016/j.taap.2008.09.020

Table 9. Genes involved in the apoptosis signaling pathway induced by sulfur mustard at 24, 72 and 168 h post-exposure.

Gene name Gene description Fold change (SM)

24 h 72 h 168 h
Akt2 v-akt murine thymoma viral oncogene homolog 2 1.78 1.46* 1.41
Bax BCL2-associated X protein 3.38 2.56 2.23
Bid BH3 interacting domain death agonist 1.97 2.54* 2.08*
Capn3 Calpain 3, (p94) 1.47 1.61 2.16
Capn5 Calpain 5 −2.20 −1.49 −2.44*
Casp8 Caspase 8, apoptosis-related cysteine peptidase 1.31 1.53* 1.72
Fas Fas (TNF receptor superfamily, member 6) 2.88 2.10* 1.89
Ikbkg Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.59* 1.80 1.48*
Map2k1 Mitogen-activated protein kinase kinase 1 1.69* 2.27* 2.02
Nfkbia Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.66* 1.43 1.62*
Nfkbie Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.66 1.99 3.97*
Pak3 p21 (CDKN1A)-activated kinase 3 −1.69 −1.70 −2.19
Pkn1 Protein kinase N1 1.61 1.35 2.48*
Rras2 Related RAS viral (r-ras) oncogene homolog 2 1.94* 1.98* 1.79
Ttk TTK protein kinase −1.24 1.04 −2.13*
*

p<0.05.

p<0.01.