Table 3.
Sequence comparison (%) between sheep CYP2J and other mammalian orthologues at the substrate recognition sites (SRS 1-6) and heme binding domain.
| Domain | Ovis aries aa residues in CYP2J | 2J2 Homo s. | 2J2 Canis f. | 2J2 Bos t. | 2J2 Macaca f. | 2J4 Rattus n. |
|---|---|---|---|---|---|---|
| Srs 1 | 109-131 | 72 | 86 | 50 | 77 | 50 |
| Srs 2 | 211-219 | 88 | 100 | 88 | 88 | 88 |
| Srs 3 | 247-254 | 78 | 66 | 66 | 88 | 66 |
| Srs 4 | 301-318 | 94 | 100 | 88 | 94 | 94 |
| Srs 5 | 373-383 | 91 | 91 | 82 | 91 | 100 |
| Srs 6 | 481-488 | 62 | 75 | 62 | 75 | 62 |
| Heme | 441-454 | 93 | 86 | 100 | 93 | 86 |
Percentage of identity with the sheep sequence.