TABLE 2.

Resistance pattern of ESBL-producing Aeromonas sp. isolates

Isolate	Aeromonas species	Clone	ESBL identified	MIC (μg/ml)b									Non-β-lactam(s) to which isolate was resistant
				CTX	FEP	CAZ	CAZ + CLAV	TIC	TIC + CLAV	ATM	ATM + CLAV	IPM
1	A. punctata	A1a	VEB-1a	8	2	32	0.25	128	16	8	<0.06	0.12	KAN, TOB, GEN, AMK, TET, NAL, CIP, FOF, CHL, SXT
2	A. punctata	A2	VEB-1a	8	4	32	0.25	128	1	8	<0.06	0.12	KAN, TOB, GEN, AMK, TET, NAL, CIP, FOF, CHL, SXT
3	A. punctata	A3	VEB-1a	4	1	32	0.06	128	0.5	2	<0.06	<0.06	KAN, TOB, AMK, TET, NAL, CIP, SXT
4	A. punctata	A3	VEB-1a	8	2	32	0.12	64	2	4	<0.06	<0.06	KAN, TOB, TET, NAL, CIP, SXT
5	A. punctata	A4	VEB-1a	4	2	16	0.25	128	128	2	<0.06	0.12	SXT
6	A. punctata	A4	VEB-1a	8	4	32	0.25	256	128	8	<0.06	0.12	SXT
7	A. allosaccharophila	B1	VEB-1a	4	2	16	0.06	32	2	2	<0.06	0.25	KAN, TOB, TET, NAL, SXT
8	A. allosaccharophila	B2	VEB-1a	8	2	16	0.06	128	16	4	<0.06	0.12	KAN, TOB, TET, NAL, CIP, SXT
9	A. veronii	C1	VEB-1a	0.25	0.12	2	0.06	16	4	0.5	<0.06	0.25	SXT
10	A. veronii	C2	VEB-1a	1	0.25	4	0.06	32	4	0.25	<0.06	0.5
11	A. media	D1	VEB-1a	32	4	32	0.5	512	512	16	<0.06	<0.06	NAL
12	A. allosaccharophila	B3	SHV-12	0.25	0.25	2	0.06	128	1	1	<0.06	0.25	NAL
13	A. allosaccharophila	B3	SHV-12	1	1	4	0.06	512	2	2	<0.06	0.25	NAL
14	A. allosaccharophila	B4	SHV-12	4	0.25	4	0.06	256	2	2	<0.06	0.25	NAL
15	A. allosaccharophila	B4	SHV-12	1	0.5	4	0.12	512	2	2	<0.06	0.25	NAL
16	A. allosaccharophila	B4	SHV-12	1	0.25	4	0.06	256	2	2	<0.06	0.25	NAL
17	A. allosaccharophila	B4	SHV-12	1	0.25	4	0.06	256	2	1	<0.06	0.25	NAL
18	A. veronii	C3	SHV-12	4	1	4	0.06	512	16	4	<0.06	0.25	NAL
19	A. veronii	C3	SHV-12	1	1	4	0.06	512	8	4	<0.06	0.25	NAL
20	A. veronii	C3	SHV-12	4	2	8	0.06	128	8	2	<0.06	0.25	NAL
21	A. media	D2	SHV-12	8	2	32	0.5	512	256	16	<0.06	<0.06	NAL, RIF, SXT
22	A. punctata	A5	PER-1	8	4	32	0.25	256	64	16	<0.06	0.12	KAN, NAL, SXT
23	A. punctata	A6	PER-1	8	4	32	0.25	128	128	16	<0.06	0.12	NAL, SXT
24	A. media	D3	PER-1	16	4	64	0.25	128	16	64	<0.06	0.12	KAN, NAL
25	A. veronii	C4	PER-6	4	2	64	0.25	128	128	32	<0.06	0.12	TET, NAL, SXT
26	A. allosaccharophila	B5	PER-6	4	0.5	2	0.06	512	64	4	<0.06	0.5	TET, NAL, SXT
27	A. allosaccharophila	B5	PER-6	4	0.5	8	2	512	512	8	0.25	0.5	TET, NAL
28	A. veronii	C4	GES-7	2	0.5	16	2	64	32	0.25	<0.06	0.25	KAN, TOB, NAL
29	A. allosaccharophila	B6	TLA-2	2	1	8	0.12	128	64	1	<0.06	0.12	NAL, RIF

^aThe letter A was arbitrarily attributed to A. punctata, B to A. allosaccharophila, C to A. veronii, and D to A. media. Different numbers correspond to different clones.

^bAbbreviations: AMK, amikacin; ATM, aztreonam; CHL, chloramphenicol; CAZ, ceftazidime; CIP, ciprofloxacin; CLA, clavulanic acid; CTX, cefotaxime; FEP, cefepime; FOF, fosfomycin; GEN, gentamicin; IPM, imipenem; KAN, kanamycin; NAL; nalidixic acid; RIF, rifampin; SXT, trimethoprim-sulfamethoxazole; SSS, sulfonamide; TET, tetracycline; TIC, ticarcillin; TOB, tobramycin.