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In vivo activity of compound 4 on infection. (A) S. aureus ARC516 in the thighs of neutropenic mice; (B) S. pneumoniae D39 in the lungs of immunocompetent mice. Results are plotted as means; the error bars represent the standard errors of the means. Dosing regimens are given in milligrams per kilogram per day. q.i.d., 4 times per day; q3, every 3 h.
