TABLE 2.

MICs and range for GPAC against 14 antibiotics

Organism (no. of strains)a	Antibiotic	MIC (mg/liter)
		Range	MIC50	MIC90
F. magna (31)	Penicillin G	0.023-0.38	0.125	0.25
	Amoxicillin-clavulanic acid	0.094-2	0.25	0.5
	Cefotetan	0.25-4	2	2
	Cefoxitin	0.38-3	1	1.5
	Ertapenem	0.016-0.19	0.064	0.125
	Meropenem	0.064-0.25	0.125	0.19
	Levofloxacin	0.094-64	0.75	64
	Moxifloxacin	0.047-64	0.19	6
	Clindamycin	0.125->256	1	3
	Metronidazole	0.094-1.5	0.38	1
	Linezolid	2-6	3	3
	Chloramphenicol	4-16	6	8
	Doxycycline	0.75-24	2	24
	Tigecycline	0.064-1	0.25	0.75
Pa. micra (27)	Penicillin G	0.016-0.125	0.016	0.047
	Amoxicillin-clavulanic acid	0.016-0.75	0.032	0.094
	Cefotetan	0.125-2	0.38	1.5
	Cefoxitin	0.125-3	0.5	2
	Ertapenem	0.008-0.19	0.047	0.125
	Meropenem	0.008-0.38	0.047	0.19
	Levofloxacin	0.125-3	0.25	0.5
	Moxifloxacin	0.094-1.5	0.19	0.38
	Clindamycin	0.047-2	0.38	1.5
	Metronidazole	0.032->256	0.094	0.25
	Linezolid	0.125-3	1	3
	Chloramphenicol	0.75-6	3	6
	Doxycycline	0.047-4	0.125	1
	Tigecycline	0.016-0.38	0.064	0.125
Pt. harei (16)	Penicillin G	0.016-0.19	0.023	0.032
	Amoxicillin-clavulanic acid	0.016-0.38	0.023	0.25
	Cefotetan	0.38-8	0.5	1
	Cefoxitin	0.023-1.5	0.094	0.5
	Ertapenem	0.006-0.023	0.012	0.016
	Meropenem	0.004-0.032	0.008	0.032
	Levofloxacin	2-64	4	6
	Moxifloxacin	0.125-1.5	0.19	0.38
	Clindamycin	0.094-1.5	0.25	1.5
	Metronidazole	0.032-2	0.38	1.5
	Linezolid	0.5-2	0.75	1.5
	Chloramphenicol	1.5-4	3	3
	Doxycycline	0.064-24	8	16
	Tigecycline	0.023-0.25	0.094	0.25
A. vaginalis (8)	Penicillin G	0.016-0.094
	Amoxicillin-clavulanic acid	0.016-0.125
	Cefotetan	0.094-0.5
	Cefoxitin	0.032-0.125
	Ertapenem	0.023-0.19
	Meropenem	0.006-0.125
	Levofloxacin	24-64
	Moxifloxacin	0.5-2
	Clindamycin	0.023->256
	Metronidazole	0.047-0.5
	Linezolid	0.38-1.5
	Chloramphenicol	1.5-3
	Doxycycline	0.125-16
	Tigecycline	0.047-1.5
Pt. ivorii (5)	Penicillin G	0.016-0.047
	Amoxicillin-clavulanic acid	0.016-0.032
	Cefotetan	0.125-1
	Cefoxitin	0.125-0.75
	Ertapenem	0.004-0.032
	Meropenem	0.002-0.016
	Levofloxacin	0.38-64
	Moxifloxacin	0.094-64
	Clindamycin	0.094-2
	Metronidazole	0.094-0.25
	Linezolid	0.19-2
	Chloramphenicol	1-3
	Doxycycline	0.064-16
	Tigecycline	0.032-0.25
Pe. anaerobius (4)	Penicillin G	0.064-2
	Amoxicillin-clavulanic acid	0.125-4
	Cefotetan	0.5-24
	Cefoxitin	0.19-3
	Ertapenem	0.032-0.75
	Meropenem	0.023-1
	Levofloxacin	0.38-1.5
	Moxifloxacin	0.19-0.25
	Clindamycin	0.032-1
	Metronidazole	0.032-0.25
	Linezolid	0.38-1.5
	Chloramphenicol	1-3
	Doxycycline	0.5-4
	Tigecycline	0.064-0.125
Pt. lacrimalis (4)	Penicillin G	0.016-0.125
	Amoxicillin-clavulanic acid	0.016-0.25
	Cefotetan	0.016-0.38
	Cefoxitin	0.016-0.25
	Ertapenem	0.002-0.012
	Meropenem	0.002-0.016
	Levofloxacin	3-8
	Moxifloxacin	0.002-0.38
	Clindamycin	0.016-0.38
	Metronidazole	0.023-0.38
	Linezolid	0.19-2
	Chloramphenicol	0.75-3
	Doxycycline	0.125-4
	Tigecycline	0.023-0.25
Pt. gorbachii (4)	Penicillin G	0.016-0.19
	Amoxicillin-clavulanic acid	0.016-0.064
	Cefotetan	0.5-1.5
	Cefoxitin	0.064-0.5
	Ertapenem	0.012-0.023
	Meropenem	0.004-0.064
	Levofloxacin	3-64
	Moxifloxacin	0.19-0.5
	Clindamycin	0.125-0.75
	Metronidazole	0.023-0.5
	Linezolid	0.75-1.5
	Chloramphenicol	2-3
	Doxycycline	0.064-0.38
	Tigecycline	0.016-0.094
A. murdochii (3)	Penicillin G	0.016-0.75
	Amoxicillin-clavulanic acid	0.032-0.25
	Cefotetan	0.75-8
	Cefoxitin	0.125-1
	Ertapenem	0.19-2
	Meropenem	0.125-0.75
	Levofloxacin	1.5-4
	Moxifloxacin	0.25
	Clindamycin	0.016-0.5
	Metronidazole	0.19-0.5
	Linezolid	0.38-0.75
	Chloramphenicol	1-3
	Doxycycline	0.25-16
	Tigecycline	0.047
At. parvulum (4)	Penicillin G	0.094-0.25
	Amoxicillin-clavulanic acid	0.064-0.25
	Cefotetan	2-8
	Cefoxitin	1.5-3
	Ertapenem	0.032-0.19
	Meropenem	0.125-0.25
	Levofloxacin	0.38-0.5
	Moxifloxacin	0.19-0.38
	Clindamycin	1.5-6
	Metronidazole	0.19-0.5
	Linezolid	0.75-2
	Chloramphenicol	4-16
	Doxycycline	1-2
	Tigecycline	0.064-0.5
A. tetradius (2)	Penicillin G	0.023-0.032
	Amoxicillin-clavulanic acid	0.032-0.064
	Cefotetan	0.25-0.5
	Cefoxitin	0.19-0.38
	Ertapenem	0.094-0.125
	Meropenem	0.094-0.125
	Levofloxacin	2-3
	Moxifloxacin	0.19-0.38
	Clindamycin	1-4
	Metronidazole	0.25-0.75
	Linezolid	1-1.5
	Chloramphenicol	3-3
	Doxycycline	2-8
	Tigecycline	0.125-0.19
Pt. octavius (1)	Penicillin G	0.125
	Amoxicillin-clavulanic acid	0.064
	Cefotetan	0.5
	Cefoxitin	0.25
	Ertapenem	0.094
	Meropenem	0.094
	Levofloxacin	4
	Moxifloxacin	0.5
	Clindamycin	0.047
	Metronidazole	0.38
	Linezolid	0.75
	Chloramphenicol	2
	Doxycycline	0.19
	Tigecycline	0.064
R. gnavus (1)	Penicillin G	1
	Amoxicillin-clavulanic acid	0.19
	Cefotetan	32
	Cefoxitin	4
	Ertapenem	0.38
	Meropenem	0.125
	Levofloxacin	64
	Moxifloxacin	6
	Clindamycin	0.38
	Metronidazole	0.094
	Linezolid	2
	Chloramphenicol	3
	Doxycycline	0.25
	Tigecycline	0.094
A. lactolyticus (1)	Penicillin G	0.125
	Amoxicillin-clavulanic acid	0.125
	Cefotetan	2
	Cefoxitin	0.5
	Ertapenem	1
	Meropenem	0.38
	Levofloxacin	6
	Moxifloxacin	0.19
	Clindamycin	0.047
	Metronidazole	0.25
	Linezolid	0.38
	Chloramphenicol	1
	Doxycycline	0.38
	Tigecycline	0.094
GPAC (4)	Penicillin G	0.023-0.125
	Amoxicillin-clavulanic acid	0.016-0.094
	Cefotetan	1-4
	Cefoxitin	0.125-1
	Ertapenem	0.006-2
	Meropenem	0.008-0.75
	Levofloxacin	0.5-2
	Moxifloxacin	0.064-0.38
	Clindamycin	0.094-0.125
	Metronidazole	0.064-0.38
	Linezolid	0.5-1
	Chloramphenicol	1.5-3
	Doxycycline	0.094-1
	Tigecycline	0.023-0.19

^aGenus abbreviations: Pe., Peptostreptococcus; Pa., Parvimonas; Pt., Peptoniphilus; A., Anaerococcus; R., Ruminococcus; At., Atopobium.