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. 2011 Jan 31;55(4):1794–1797. doi: 10.1128/AAC.01757-10

TABLE 2.

Voriconazole MICs according to EUCAST fluconazole breakpointsa

Species Voriconazole MIC (mg/liter) for indicated fluconazole susceptibility categoryb
S (n = 3,247)
I (n = 261)
R (n = 718)
MIC50 MIC90 Range MIC50 MIC90 Range MIC50 MIC90 Range
Candida albicans 0.015 0.015 0.015-1.0 0.03 1.0 0.015-1.0 0.25 >8.0 0.015->8.0
Candida parapsilosis 0.015 0.03 0.015-0.12 0.12 0.25 0.015-0.25 0.25 2.0 0.03->8.0
Candida tropicalis 0.015 0.06 0.015-0.50 0.25 2.0 0.015-2.0 2.0 >8.0 0.015->8.0
Candida glabrata 0.06 0.25 0.015-0.50 0.12 0.25 0.03-0.50 0.25 4.0 0.015->8.0
Candida kruseic 0.25 1.0 0.015-4.0
Total 0.015 0.03 0.015-0.50 0.12 0.25 0.015-2.0 0.50 4.0 0.015->8.0
a

See reference 17.

b

S, fluconazole-susceptible strains (MIC ≤ 2); I, fluconazole-intermediate strains (MIC = 4); R, fluconazole-resistant strains (MIC > 8); MIC50, concentration causing inhibition of 50% of isolates; MIC90, concentration causing inhibition of 90% of isolates.

c

C. krusei is intrinsically resistant to fluconazole.