FIG. 2.

The antimicrobial resistance gene content of 32 plasmids carrying qnrS. (a) Graph showing the proportional relationships of transformants demonstrating hybridization to 25 specific antimicrobial resistance genes and one class one integrase gene (intl1). The graph is subdivided into those plasmids that were isolated in the community (black bars) (n = 21) and those that were isolated in the hospital (gray bars) (n = 11). The labels at the top of the diagram highlight the group to which the indicated antimicrobial resistance gene confers resistance. (b) Neighbor-joining tree representing DNA hybridization to the antimicrobial resistance gene microarray. The 32 strains fall into main clusters A and B, which are distinguished by light and dark gray shading. Asterisks identify those strains containing community plasmids; the numbers adjacent to the strain names correspond to the EcoRI restriction digestion results (Fig. 1). The numbers on each branch correspond to percent identity between individual branches.