TABLE 2.
Kinetic parameters for inhibition of GES enzymes by clavulanic acid
| Enzyme | Mean ± SD |
Partition ratio | |
|---|---|---|---|
| Ki (μM) | kclav (s−1) | ||
| GES-1 | 49 ± 4 | 0.023 ± 0.001 | ∼300 |
| GES-2 | 5.0 ± 0.8 | 0.082 ± 0.005 | ∼20 |
| GES-5 | 39 ± 2 | 0.015 ± 0.001 | ∼450 |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.