TABLE 5.

Frequency of spontaneous resistance to BAL30376

Organism	Inoculum (CFU)	Compound	Highest concn at which growth occurred (mg/liter)	Frequency
A. baumannii HPA74510	109	BAL30376	No resistant colonies
A. junii 15218	109	BAL30376	No resistant colonies
		Meropenem	1	10−6.8
E. cloacae R947	109	BAL30376	8	10−6.2
		Meropenem	16	10−5.2
K. pneumoniae CF104	109	BAL30376	No resistant colonies
		Meropenem	No resistant colonies
		Ceftazidime	No resistant colonies
		Cefepime	No resistant colonies
P. aeruginosa BA	109	BAL30376	16	10−7.7
		Meropenem	16	10−6.8
		Ceftazidime	16	10−6.5
		Cefepime	16	10−5.9
P. aeruginosa 860	107	BAL30376	16	10−6.3
		Meropenem	No resistant colonies
		Ceftazidime	16	10−3.4
		Cefepime	16	10−4.0
P. aeruginosa 6067	107	BAL30376	16	10−3.9
		Meropenem	8	10−5.3
P. aeruginosa (560546)9 M.P.	107	BAL30376	16	10−5.4
		Meropenem	8	10−6.1
S. maltophilia 1AC736	109	BAL30376	No resistant colonies
		Ceftazidime	16	10−6.4