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. 2011 Jan 31;55(4):1420–1427. doi: 10.1128/AAC.01253-10

FIG. 3.

FIG. 3.

Mean bacterial densities over 48 h for KPC-producing Klebsiella pneumoniae isolates with a tigecycline MIC of 2 μg/ml and a meropenem MIC of 16 μg/ml. (A) Monotherapy models. Thick solid line, control; closed circles, tigecycline (isolate 358); open circles, tigecycline (isolate 360); closed triangles, meropenem (isolate 358); open triangles, meropenem (isolate 360). (B) Combination therapy models. Thick solid line, control; closed squares, tigecycline and meropenem (isolate 358); open squares, tigecycline and meropenem (isolate 360). The lower limit of detection (dashed line) was set to 101 CFU/ml.