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. 2011 Jan 31;55(4):1543–1548. doi: 10.1128/AAC.01510-09

TABLE 2.

Median ΣFICs of antifungal drug combinations for five Candida strains calculated from visual readings reported by eight participating laboratories

Antifungal drug combination Median ΣFIC (% agreement/correlation coefficient)
C. parapsilosis (ATCC 22019) C. albicans 20533.043 C. albicans 20464.007 C. glabrata 20205.075 C. parapsilosis 20580.070
AMB-AND 0.56 (37.5/0.42) 0.79 (75.0/0.82) 0.56 (62.5/0.88) 0.84 (75.0/0.86) 0.38 (75.0/0.62)
AMB-CSP 0.62 (62.5/0.54) 0.74 (37.5/0.29) 0.53 (75.0/0.85) 1.18 (62.5/0.65) 0.49 (62.5/0.56)
AMB-MCF 0.51 (87.5/0.96) 1.06 (37.5/0.48) 0.53 ((50.0/0.67) 1.06 (87.5/0.91) 0.56 (50.0/0.69)
AMB-PSC 0.74 (37.5/0.18) 0.59 (75.0/0.51) 0.53 (87.5/0.97) 0.46 (37.5/0.32) 0.50 (87.5/0.95)
AMB-VRC 1.045 (0.0/0.48) 0.51 (87.5/0.91) 0.57 (50.0/0.64) 0.63 (37.5/0.31) 1.06 (37.5/0.29)
AND-CSP 0.56 (87.5/0.86) 1.00 (75.0/0.68) 0.56 (25.0/0.26) 1.75 (87.5/0.91) 0.78 (37.5/0.42)
AND-MCF 0.62 (75.0/0.63) 1.75 (75.0/0.41) 0.74 (75.0/0.89) 1.5 (75.0/0.68) 0.84 (50.0/0.48)
AND-PSC 0.51 (37.5/0.29) 0.81 (37.5/0.18) 0.49 (37.5/0.44) 0.76 (62.5/0.57) 0.50 (50.0/0.30)
AND-VRC 1.06 (25.0/0.18) 0.79 (50.0/0.46) 0.80 (37.5/0.29) 0.76 (87.5/0.82) 1.01 (37.5/0.34)
CSP-MCF 0.65 (87.5/0.90) 1.31 (50.0/0.56) 0.44 (75.0/0.69) 2.00 (75.0/0.58) 0.81 (37.5/0.26)
CSP-PSC 0.62 (87.5/0.87) 1.01 (75.0/0.85) 0.49 (87.5/0.98) 1.01 (62.5/0.36) 1.00 (87.5/0.98)
CSP-VRC 1.06 (50.0/0.28) 1.51 (37.5/0.25) 0.75 (62.5/0.60) 1.00 (75.0/0.33) 1.18 (12.5/0.26)
MCF-PSC 0.78 (37.5/0.17) 1.01 (62.5/0.58) 0.78 (75.0/0.68) 1.00 (50.0/0.58) 1.06 (25.0/0.27)
MCF-VRC 1.03 (75.0/0.62) 1.01 (62.5/0.76) 0.75 (25.0/0.18) 1.00 (50.0/0.33) 1.03 (50.0/0.68)
PSC-VRC 1.12 (50.0/0.42) 1.00 (75.0/0.82) 0.74 (25.0/0.13) 0.75 (87.5/0.73) 1.50 (25.0/0.29)