TABLE 2.
Antifungal drug combination | Median ΣFIC (% agreement/correlation coefficient) |
||||
---|---|---|---|---|---|
C. parapsilosis (ATCC 22019) | C. albicans 20533.043 | C. albicans 20464.007 | C. glabrata 20205.075 | C. parapsilosis 20580.070 | |
AMB-AND | 0.56 (37.5/0.42) | 0.79 (75.0/0.82) | 0.56 (62.5/0.88) | 0.84 (75.0/0.86) | 0.38 (75.0/0.62) |
AMB-CSP | 0.62 (62.5/0.54) | 0.74 (37.5/0.29) | 0.53 (75.0/0.85) | 1.18 (62.5/0.65) | 0.49 (62.5/0.56) |
AMB-MCF | 0.51 (87.5/0.96) | 1.06 (37.5/0.48) | 0.53 ((50.0/0.67) | 1.06 (87.5/0.91) | 0.56 (50.0/0.69) |
AMB-PSC | 0.74 (37.5/0.18) | 0.59 (75.0/0.51) | 0.53 (87.5/0.97) | 0.46 (37.5/0.32) | 0.50 (87.5/0.95) |
AMB-VRC | 1.045 (0.0/0.48) | 0.51 (87.5/0.91) | 0.57 (50.0/0.64) | 0.63 (37.5/0.31) | 1.06 (37.5/0.29) |
AND-CSP | 0.56 (87.5/0.86) | 1.00 (75.0/0.68) | 0.56 (25.0/0.26) | 1.75 (87.5/0.91) | 0.78 (37.5/0.42) |
AND-MCF | 0.62 (75.0/0.63) | 1.75 (75.0/0.41) | 0.74 (75.0/0.89) | 1.5 (75.0/0.68) | 0.84 (50.0/0.48) |
AND-PSC | 0.51 (37.5/0.29) | 0.81 (37.5/0.18) | 0.49 (37.5/0.44) | 0.76 (62.5/0.57) | 0.50 (50.0/0.30) |
AND-VRC | 1.06 (25.0/0.18) | 0.79 (50.0/0.46) | 0.80 (37.5/0.29) | 0.76 (87.5/0.82) | 1.01 (37.5/0.34) |
CSP-MCF | 0.65 (87.5/0.90) | 1.31 (50.0/0.56) | 0.44 (75.0/0.69) | 2.00 (75.0/0.58) | 0.81 (37.5/0.26) |
CSP-PSC | 0.62 (87.5/0.87) | 1.01 (75.0/0.85) | 0.49 (87.5/0.98) | 1.01 (62.5/0.36) | 1.00 (87.5/0.98) |
CSP-VRC | 1.06 (50.0/0.28) | 1.51 (37.5/0.25) | 0.75 (62.5/0.60) | 1.00 (75.0/0.33) | 1.18 (12.5/0.26) |
MCF-PSC | 0.78 (37.5/0.17) | 1.01 (62.5/0.58) | 0.78 (75.0/0.68) | 1.00 (50.0/0.58) | 1.06 (25.0/0.27) |
MCF-VRC | 1.03 (75.0/0.62) | 1.01 (62.5/0.76) | 0.75 (25.0/0.18) | 1.00 (50.0/0.33) | 1.03 (50.0/0.68) |
PSC-VRC | 1.12 (50.0/0.42) | 1.00 (75.0/0.82) | 0.74 (25.0/0.13) | 0.75 (87.5/0.73) | 1.50 (25.0/0.29) |