TABLE 3.

Median ΣFICs of antifungal drug combinations for five Candida strains calculated from spectrophotometric readings reported by seven participating laboratories

Antifungal drug combination	Median ΣFIC (% agreement/correlation coefficient)
	C. parapsilosis (ATCC 22019)	C. albicans 20533.043	C. albicans 20464.007	C. glabrata 20205.075	C. parapsilosis 20580.070
AMB-AND	0.53 (42.8/0.44)	0.81 (83.3/0.98)	0.46 (85.7/0.84)	1.04 (57.1/0.44)	0.20 (42.8/0.24)
AMB-CSP	0.56 (85.7/0.91)	0.90 (91.6/0.99)	0.56 (42.8/0.29)	1.06 (14.2/0.15)	0.43 (100/0.99)
AMB-MCF	0.42 (14.3/0.31)	1.06 (57.1/0.60)	0.67 (85.7/0.80)	1.06 (100/0.99)	0.40 (100/0.95)
AMB-PSC	1.04 (42.8/0.43)	0.59 (71.4/0.78)	0.56 (85.7/0.87)	0.35 (42.8/0.22)	0.59 (85.1/0.84)
AMB-VRC	1.01 (57.1/0.83)	0.51 (28.6/0.19)	0.59 (57.1/0.53)	0.38 (57.1/0.56)	1.04 (57.1/0.51)
AND-CSP	0.56 (100/0.99)	1.06 (57.1/0.67)	0.56 (42.8/0.49)	1.75 (100/0.99)	0.56 (14.2/0.24)
AND-MCF	0.56 (14.2/0.25)	1.75 (91.6/0.92)	0.56 (42.8/0.17)	1.75 (71.4/0.76)	0.65 (85.7/0.96)
AND-PSC	0.56 (100/0.99)	0.77 (71.4/0.76)	0.90 (85.7/0.97)	1.01 (72.8/0.57)	0.76 (85.7/0.87)
AND-VRC	1.06 (14.2/0.16)	0.76 (42.9/0.48)	0.77 (85.7/0.98)	0.76 (85.7/0.87)	1.01 (57.1/0.51)
CSP-MCF	0.62 (57.1/0.63)	1.31 (42.9/0.48)	0.55 (85.7/0.78)	2.00 (100/0.96)	0.56 (85.7/0.89)
CSP-PSC	0.56 (100/0.99)	1.02 (28.6/0.15)	0.68 (85.7/0.99)	1.01 (100/0.99)	0.68 (100/0.99)
CSP-VRC	1.06 (57.1/0.61)	1.02 (28.6/0.32)	0.76 (71.4/0.90)	1.01 (100/0.99)	1.04 (57.1/0.68)
MCF-PSC	1.01 (57.1/0.52)	1.02 (14.2/0.11)	0.76 (57.1/0.61)	1.01 (57.1/0.50)	1.03 (100/0.98)
MCF-VRC	0.76 (71.4/0.85)	1.02 (57.1/0.49)	0.75 (85.7/0.83)	1.01 (100/0.97)	1.03 (28.6/0.48)
PSC-VRC	1.37 (85.7/0.84)	0.52 (83.3/0.81)	0.76 (85.7/0.88)	0.76 (42.8/0.36)	1.50 (14.2/0.25)