TABLE 2.

MICs for Cryptococcus neoformans obtained with each medium^a

Antifungal	CLSI method		EUCAST method		EUCAST method at 30°C with shaking		EUCAST method at 30°C		YNB shaken		YNB static
	GM	Min-max	GM	Min-max	GM	Min-max	GM	Min-max	GM	Min-max	GM	Min-max
AmB	0.13	0.06-0.25	0.35	0.25-0.50	0.31	0.12-0.50	0.06	0.03-0.12	0.44	0.25-1	0.41	0.25-0.50
Flucytosine	3.73	2-4	6.50	1-16	9.85	8-16	6.50	2-16	16	8-32	7.46	1-16
Fluconazole	2.46	0.25-8	4.59	0.50-16	8	0.50-16	4.92	1-32	5.66	0.50-16	2.46	0.50-8
Itraconazole	0.09	0.015-0.25	0.07	0.015-0.25	0.05	0.015-0.25	0.08	0.015-0.50	0.18	0.03-4	0.08	0.015-0.25
Voriconazole	0.07	0.015-0.25	0.06	0.015-0.25	0.15	0.015-0.50	0.07	0.015-0.25	0.07	0.015-0.25	0.06	0.015-0.12
Posaconazole	0.16	0.015-0.25	0.11	0.03-0.25	0.17	0.03-0.50	0.05	0.03-0.25	0.21	0.015-8	0.10	0.03-0.25
Caspofungin	>16	16-32	16	8->16	>16	16->16	>16	16->16	>16	16->16	>16	8->16
Micafungin	>16	16-32	>16	>16->16	>16	>16->16	>16	>16->16	>16	>16->16	>16	>16->16
Anidulafungin	>16	32-32	>16	0.06->16	>16	>16->16	>16	4->16	>16	16->16	>16	>16->16

^aAmB, amphotericin B; GM, geometric mean.